This video segment from A Science Odyssey profiles Dr. Joseph Goldberger and his search for a cure for pellagra, a poorly understood disease that ravaged the American South in the early 1900s. Pellagra's symptoms—a skin rash that preceded confusion, hallucinations, and insanity—ultimately caused death in tens of thousands of people. In investigating the cause, Goldberger analyzed the diets of the victims and hypothesized that their foods lacked essential vitamins. Although he conducted experiments that supported his hypothesis, Goldberger's findings were not accepted until after his death.
This resource was adapted from the A Science Odyssey: A Matter of Life and Death.